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Funding for our Inflam-EPR project

posted Sep 7, 2012, 1:34 AM by Yann Le Du   [ updated Sep 7, 2012, 5:55 AM ]
University Pierre et Marie Curie (Paris 6, UPMC) is funding our Inflam-EPR MECV project. It involves teams of medical doctors, chemists and computer scientists.

This project has two goals: first, to develop a new methodology based on Electron Paramagnetic Resonance (EPR) to quantify the in vivo production of reactive oxygen species (ROS) in pathological tissues; second, to show the adequacy of such an approach for the understanding of chronic inflammatory mechanisms. Two mouse experimental models will be assessed, which differ both in the targeted organ and in the inflammatory process.

The MECV funding will allow us to demonstrate the feasibility of investigations, opening the way to more ambitious projects leading to applications in human pathology. In particular, the development of an EPRI spectrometer is already planned within the next four years for use at the HEGP hospital, and this MECV project proposal is an important step on the path to generalized use of EPR in human pathology studies.